Natural Options to Reverse Parkinsons Symptoms

Category: fatigue

Cannabidiol CBD Offers Relief from Parkinson’s Symptoms

As my video preview below explains, studies report that Cannabidiol CBD offers relief from Parkinson’s symptoms. Annual Parkinsons Recovery surveys also report success with reversing Parkinson’s symptoms when taking CBD oil. It is one of the most frequently listed therapies reported to be useful to members of the Parkinsons Recovery audience.

CBD stands for “cannabidiol oil”. It is extracted from either the Hemp plant or the Marijuana plant. Using CBD allows the medical benefits of medical marijuana without the high that is associated with THC. CBD in itself has no psychedelic properties and is considered safe for consumption
 

Abstracts of recent CBD studies and posted at the bottom of this post. Taken together, studies find that CBD …

  • Protects dopaminergic neurons
  • Reduces neuro-inflammation and oxidative stress
  • Improves motor symptoms
  • Increases REM sleep
  • Reduces insomnia episodes
  • Enhances mood
  • Reduces fatigue
  • Reduces chronic pain
  • Helpful for stroke victims.

About Alovea Entourage Cannabidiol CBD

Alovea Entourage contain plant-derived cannabinoids, distinct from endocannabinoids that are produced in the body and synthetic cannabinoids. It includes Acemannan, an extract from the Aloe plant, to help the body’s management of mood, memory, sleep and joint health.

SYMBIOTIC IMMUNE SUPPORT

There are many products that have been formulated with additional ingredients to provide support for specific benefits like improved sleep, mood and joint health. One of the most profound impacts has come from the addition of immune modulating aloe vera Acemannan.

Combining the immune modulating fractions of Acemannan with high quality CBD hemp oil provides a symbiotic impact (1 + 1 = 4) that can dramatically enhance overall immune support.

PATENT-PENDING FORMULA INCLUDES:

  • Organic Broad Spectrum Hemp Oil
  • Super critical CO2 extraction
  • Each batch tested to ensure 0.0% THC
  • Absorption increased by 5-7 times over other hemp oil products with water compatible nanotechnology
  • Enhanced Entourage Effect through proprietary terpene blend
  • Symbiotic effect with the highest rated immune modulating Alovéa AE (Acemannan Extract)
  • Wonderful cinnamon and tropical flavors!

Recent CBD (Cannabidiol) Research Studies

Clinical research on CBD (cannabidiol) includes studies of anxiety, cognition, movement disorders, and pain. Abstracts of recent studies are included below.

Pharmaceuticals (Basel). 2026 Feb 17;19(2):330. Cannabidiol in Neurology: Current Insights and Translational Perspectives

Abstract

Cannabidiol (CBD) is one of the most studied compounds of Cannabis sativa and has attracted significant interest due to its therapeutic and beneficial properties, which have been confirmed in numerous preclinical and clinical studies over the last few years.

A great advantage of CBD over the other widely known Cannabis sativa ingredient, ?-9-tetrahydrocannabinol (THC), is that CBD does not exert intoxicating and psychoactive effects, making it an attractive candidate for therapeutic applications in neurological disorders.

CBD has been shown to exert antioxidant, analgesic, anti-inflammatory, and neuroprotective effects, with therapeutic potential for various neurological conditions. To date, the only drug that consists solely of highly purified CBD is Epidiolex, which is used in the management of severe forms of epilepsy such as Dravet syndrome and Lennox-Gastaut syndrome. Another legal medication containing CBD (albeit with the addition of THC) is Sativex, used to alleviate spasticity in multiple sclerosis.

Besides epilepsy, preclinical data suggest that CBD alone may be potentially beneficial in treating chronic pain, multiple sclerosis, Alzheimer’s and Parkinson’s diseases, or stroke.

The safety profile of CBD is generally considered favorable, as the most commonly reported adverse effects are mild (e.g., somnolence, diarrhea).

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Cannabis Cannabinoid Res. 2026 Feb;11(1):11-29. Unveiling Neurological Benefits: A Review of Hemp Leaf, Flower, Seed Oil Extract, and Their Phytochemical Properties in Neurological Disorders

Abstract

Neurological disorders such as epilepsy, Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis present significant global health care challenges, with complex pathophysiology and limited therapeutic options that often carry substantial side effects.

Hemp-derived compounds, particularly from Cannabis sativa seeds, leaves, and flowers, have gained attention for their potential neuroprotective properties. This review aims to synthesize the current evidence surrounding the therapeutic benefits of hemp-derived compounds, focusing on their bioactive phytochemical profiles, mechanisms of action, and therapeutic efficacy in treating neurological disorders.

A comprehensive review of pre-clinical and clinical studies was conducted, analyzing the phytochemical composition of hemp extracts, including cannabinoids (such as cannabidiol, CBD), terpenes, flavonoids, and polyunsaturated fatty acids. We explored their mechanisms of action through interactions with the endocannabinoid system, neurotransmitter receptors, inflammatory pathways, and oxidative stress mechanisms.

The review highlights the therapeutic potential of hemp-derived extracts in mitigating various neurological conditions. Pre-clinical and clinical studies have demonstrated their efficacy in reducing seizure frequency in epilepsy, protecting dopaminergic neurons in Parkinson’s disease, alleviating neuroinflammation and oxidative stress in Alzheimer’s disease, and promoting remyelination in multiple sclerosis.

The entourage effect, where cannabinoids, terpenes, and flavonoids work synergistically, enhances these therapeutic effects. Innovations in extraction technologies have optimized yield and preserved bioactivity, further enhancing clinical relevance.

Hemp-derived compounds exhibit significant neuroprotective and therapeutic potential for managing neurological disorders.

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J Clin Sleep Med. 2025 Jan 1;21(1):69-80. Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, crossover study

Abstract

Study objectives: Cannabidiol (CBD) is increasingly used as a health supplement, though few clinical studies have demonstrated benefits. The primary objective of this study was to evaluate the effects of an oral CBD-terpene formulation on sleep physiology in individuals with insomnia.

Methods: In this double-blind, placebo-controlled, randomized clinical trial, 125 individuals with insomnia received an oral administration of CBD (300 mg) and terpenes (1 mg each of linalool, myrcene, phytol, limonene, ?-terpinene, ?-terpineol, ?-pinene, and ?-caryophyllene) for ? 4 days/wk over 4 weeks using a crossover design. The study medication was devoid of ?9-tetrahydrocannabinol. The primary outcome measure was the percentage of time participants spent in the combination of slow-wave sleep (SWS) and rapid eye movement (REM) sleep stages, as measured by a wrist-worn sleep-tracking device.

Results: This CBD-terpene regimen marginally increased the mean nightly percentage of time participants spent in SWS + REM sleep compared to the placebo (mean [standard error], 1.3% [0.60%]; 95% confidence interval, 0.1-2.5%; P = .03).

More robust increases were observed in participants with low baseline SWS + REM sleep, as well as in day sleepers. For select participants, the increase in SWS + REM sleep averaged as much as 48 minutes/night over a 4-week treatment period. This treatment had no effect on total sleep time, resting heart rate, or heart rate variability, and no adverse events were reported.

Conclusions: Select CBD-terpene ratios may increase SWS + REM sleep in some individuals with insomnia and may have the potential to provide a safe and efficacious alternative to over-the-counter sleep aids and commonly prescribed sleep medications.

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J Obstet Gynaecol Can. 2025 Jul;47(7):102839. Cannabidiol Use and Perceptions of Effectiveness in Women With Chronic Pelvic Pain

Abstract

Objectives: To investigate cannabidiol (CBD) use in women with chronic pelvic pain and nociplastic pain, as represented by a diagnosis of fibromyalgia, including impact on pain and associated symptoms, substitutions for other medications, and side effects.

Methods: This was a cross-sectional study using data derived from an online survey distributed through the National Fibromyalgia Association between April and May of 2020. This secondary analysis was limited to participants with concurrent chronic pelvic pain diagnoses. Participants were asked about their history of CBD use and sub-grouped by use patterns.

Results: Of 1382 included participants, 501 (36.3%) were in the “Never Use” group, 404 (29.2%) were in the “Past Use” but not “Current Use” group and 477 (34.5%) were in the “Current Use” group. Of 477 participants in the “Current Use” group, 80.9% (n = 386) reported pain improvement. The most common indications for current CBD use were pain, insomnia, and anxiety. Participants who reported pain improvement were more likely to report improved sleep (P < 0.001), anxiety (P < 0.001), depression (P = 0.001), fatigue (P < 0.001), overall health (P < 0.001), and substitution of CBD for at least 1 other medication (P = 0.003) than those who reported no pain improvement. About half of the participants reported side effects, most of which were minor with the most common being drowsiness (n = 138, 29%).

Conclusions: Two-thirds of participants with concurrent chronic pelvic pain and fibromyalgia have used CBD. Improved pain with CBD use correlated with improvement in other symptom domains, such as sleep, mood, fatigue, and overall health. A large proportion of those using CBD reported substituting it for higher-risk medications.

Cannabis Cannabinoid Res. 2023 Oct;8(5):716-730.Cannabinoids in Treating Parkinson’s Disease Symptoms: A Systematic Review of Clinical Studies


Abstract

Background: Parkinson’s disease (PD) is a serious neurodegenerative condition impacting many individuals worldwide. There is a need for new non-invasive treatments of PD. Cannabinoids in the form of cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) may offer utility as treatment, and our objective was hence to conduct a systematic review regarding the clinical evidence for the efficacy and safety of cannabinoids in treating PD.

Methods: Screening, data extraction, and quality assessments were all conducted by multiple reviewers, with discrepancies resolved by consensus.

Results: After conducting searches in 4 different databases, 673 articles were screened. Thirteen articles were deemed eligible for inclusion in this review. It was shown that cannabis, CBD, and nabilone (a synthetic form of THC) were capable of consistently improving motor symptoms more than a placebo. All treatments improved various non-motor symptoms, particularly with cannabis improving pain intensity, and CBD improving psychiatric symptoms in a dose-dependent manner. Adverse effects were usually minor, and, in the case of CBD, rare (except at very high doses).

Conclusion: Cannabinoids have been shown to safely offer important potential in treating motor symptoms in PD and some non-motor symptoms.

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery ®
https://www.parkinsonsrecovery.com
robert@parkinsonsrecovery.com

Remedy for Depression and Fatigue

Is there a remedy for depression and fatigue?
I have it all the time.What can I do about it?

More and more scientists and looking at inflammation
as a contributing factor to many chronic conditions. In the
case of Parkinson’s, it makes logical sense to speculate
that neural networks function poorly when the tissues
connected with the neurons are swollen.

Think about how you feel when you eat too much.
I personally feel bloated, sluggish, blocked and immobile.
All I can do until some of the food is digested is to sit up
straight and pray I do not have to move for a while.
Meditation is a choice, but I usually fall asleep.

This is precisely how neurons feel when they become
swollen. Give your neurons a break. They have feelings
themselves you know. There is not enough room for
the neural networks to function when the tissues are
swollen. Electrical pathways become obstructed.

The distribution of hormones to your muscles
and tissues also becomes difficult when inflammation
is present. The tissues throughout your your body
are busy handling another emergency.
They have little space to receive the sweetness
of any uninvited hormonal visitations. A natural remedy for
depression and fatigue is not what you would expect: Get
inflammation under control.

It is like seeing two friends having a huge fight. They are both
furious at one another. As their friend who is witness to the fight,
you try to squeeze in a word or two, but your friends ignore you.
They are too preoccupied with their own fight. In a similar fashion,
hormones have difficult squeezing themselves into tissues that
are inflamed.

When all of the healthy cells function at their peak levels,
you will feel better and find relief from the symptoms of
Parkinson’s. Conversely, you will certainly feel worse
when the tissues in your body are inflamed. Depression
creeps in. Fatigue becomes a way of life. What then is a
natural remedy for depression and fatigue if inflammation
is the issue?

OK. Inflammation causes problems. What can I do
about it? When I exercise for a long time the tissues
in my body become inflamed. I often take one ibuprofen.
It reduces the inflammation in several hours, but
taking ibuprofen imposes a potentially life threatening
challenge to the kidneys. So ibuprofen is not a long
term solution.

Consider another possibility. Perhaps the
tissues in your body have always been inflamed.
Since you do not know any other way to feel,
you have become used to feeling lousy.
It is the only way you have ever known.

Why then are the tissues in your body always
inflamed? You may be allergic to a certain food
(or foods) that you love to eat. A hidden source
of inflammation for most people is allergic
reactions to something they put into their bodies.

How do you know if you are allergic to any foods.
And, if you are allergic, how do your figure out which
foods they might be?

It is very easy to know. Stop eating the foods you
suspect that may be causing the inflammation
for two weeks. See if you feel better. This sounds
easy, but it is anything but easy. Let me explain why.

Let us consider one food by way of example: ice cream.
I love eating ice cream myself. Here is my conversation
with myself (and I am not making this up).

“Maybe the inflammation is being cause by eating
ice cream. Oh, I think not. After all, when I eat
ice cream I do not get sick. I do not have rashes.
I do not have stomach aches. I do not sweat or
puke or turn purple. It it must not be ice cream.”

Being the logical person that I am, I continue eating
ice cream. I stop eating turnips instead to see if turnips
might be the problem. They are not. All is well. I still get
to eat the ice cream.

There is a double twist to my logic. My body has
become acclimated to processing and digesting
ice cream. If you also love to eat ice cream, you
have probably liked eating ice cream since you
were a child. As an incredibly cleaver living entity,
the body quickly learns how to turn on systems
that reduce the allergic reactions to ice cream.
In other words, the true symptoms are masked when
we eat ice cream regularly.

You thus conclude “I do not feel that bad when
I eat ice cream.”

In one sense this is true. In another sense you
would be feeling so much better if you stopped
eating ice cream and started eating healthy
substitutes.

Because you have always eaten ice cream
your entire life, the truth is that you have
actually always felt lousy. You just did not
know it. It is the only way you have ever
felt – lousy.

When crying out for a natural remedy for depression and
fatigue have you ever heard yourself say,

“I seem to be so depressed all the time.”

“I drag every day of the week.”

There it is.

Because you become acclimated to feeling tired
and depressed, you forget what it is like to feel
good. The only way to know if a food is causing
fatigue, inducing depression and entangling neural
networks is to stop eating that particular food for
at least two weeks. In my example, the test is to
stop eating ice cream for two weeks.

Acknowledge the source of Inflammation to get the 
Natural Remedy for Depression and Fatigue 

Then, eat a lot of ice cream one day.
Indulge yourself. Reward yourself for doing
the test. Eat a quart or two of your
favorite ice cream. Make it three. Then see
how you feel. If  you notice a flare up of
fatigue and depression after eating the ice
cream you can almost certainly conclude
that ice cream is causing inflammation
in your body.

I report this truth with such detachment
as if it has never happened to me. But it
has and it did. My naturopath muscle tested
me for various food items and suspected
that I had allergies to dairy. I love eating
cheese. I love chocolate milkshakes.

“I am OK when I eat these foods.
I love them. That can not be the problem.”

Did I stop eating milkshakes for two weeks?
Of course not. I convinced myself that I was
actually very healthy and that I deserved
a little pleasure in my life. My naturopath
got the wrong result.

After fighting this battle for years, I finally
did the gold standard test for allergies.
I did not drink milk shakes for two weeks straight.
The anticipation of being able to have a milk shake
became more and more intense with each passing
day until day 15 arrived when I ate two milk shakes,
one chocolate and one vanilla. They were
thoroughly yummy as always.

I paid a dear price for those few minutes of bliss.
I became seriously depressed for several days. The fatigue
was overwhelming. I really just wanted to sleep and
forget about working or playing. I was miserable.

The truth is that I did not realize how tired and depressed
the ice cream was making me until I gave my body a chance
to detox itself from dairy. After 14 days of not eating ice cream
the inflammation that was literally always present
in my tissues had subsided.

My experiment was a success. When I added back into
my body the dairy, my body told me in no uncertain
terms that it could not tolerate dairy. I now know this is
why I had constant ear aches as a child.

Of course I did not like the outcome, but excellent
substitutes for dairy do exist.

If you have Parkinson’s you need energy to feel better.
It is hard to do the things that will make you feel better
if you are depressed or if you are tired all the time.
It is thus highly probably that a big reason why you feel
bad is because of food that you are eating.

My problem is dairy. Your problem may be wheat or
corn or soy or whatever. Give the experiment a try
and see what you can discover for yourself. Most people
are allergic to something. They just do not know it.

The test is free. It requires only determination and
discipline. The end result can have a huge impact on
how you feel.

So, explore this natural remedy for depression and figure.
Say goodbye to depression and fatigue.
Say hello to life.

Robert Rodgers, Ph.D.
Founder 2004
Parkinsons Recovery

© Parkinsons Recovery