In a study published in 2026 posted below, we have still more evidence for the benefits of exercise for individuals experiencing the neurological challenges of Parkinsons. Results of this study found that an eight-week aerobic resistance training program improved tremor and walking endurance in patients with Parkinson’s symptoms.
NeuroRehabilitation. 2026 Apr 10:10538135261434253. Effects of an 8-Week Combined Aerobic Resistance Training on Motor Function, Functional Mobility, and Metabolic Parameters in Patients with Parkinson’s Disease: A Controlled Study
Abstract
Exercise is increasingly recognized as a key component of Parkinson’s disease (PD) management, but data on short-term combined aerobic-resistance training (ART) on motor and metabolic parameters remain limited.
In this controlled study, 28 patients with PD (median Hoehn & Yahr stage= 2, IQR 1.75-2.0) were allocated to an 8-week supervised aerobic-resistance training ART group (n= 19) or a stretching-only control group (n = 9). Training consisted of two 45-minute sessions weekly. Primary outcomes were MDS-UPDRS-III, Sit-to-Stand Test (STS), and Six-Minute Walk Test (6MWT).
Fasting laboratory parameters were exploratory given the small sample size and absence of an a priori power analysis. Between-group post-intervention differences were analyzed using ANCOVA (baseline as covariate); exploratory biochemical outcomes were controlled for multiple comparisons using Benjamini-Hochberg false discovery rate (FDR).
ART improved the MDS-UPDRS-III tremor subscore (p = 0.004) and6MWT distance (p = 0.003), with no significant effects on other motor or functional outcomes. In exploratory laboratory analyses, unadjusted between-group differences were observed for HDL cholesterol (p =0.014), vitamin D3 (p = 0.003), TSH (p = 0.042), and homocysteine (p =0.019); after FDR correction, only vitamin D3 remained significant (qFDR= 0.039). Total cholesterol, LDL, and VLDL showed non-significant decreases.
An eight-week ART program improved tremor and walking endurance inpatients with PD, while other motor outcomes remained unchanged. Exploratory changes in selected biochemical markers were detected (including a decrease in vitamin D3).
Robert Rodgers PhD
Founder 2004
Parkinsons Recovery®
https://www.parkinsonsrecovery.com
robert@parkinsonsrecovery.com




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