One predictor that an individual will develop symptoms associated with a diagnosis of Parkinsons is the loss of the ability to smell. Many people with Parkinsons believe that remedies for loss of smell do not exist. The belief is that once smell is lost it is a done deal.
I suggest the body can always recover problematic symptoms by identifying and addressing the root cause or causes. One deficiency documented to be deficient in persons with Parkinsons symptoms is zinc which – you probably guessed it – is related to a loss of smell and an increased risk of dementia.
Zinc deficiencies can also cause a compromised immune system, hair loss and even a loss of appetite. Adequate levels of zinc protect against oxidative stress and the aggregation of the protein alpha-synuclein.
Most importantly, zinc helps regulate blood sugar levels which have been found problematic in persons with Parkinsons. It reduces the impact of insulin resistance and helps improve regulation of sugar levels.
A word of caution. While too little zinc causes a variety of symptoms an excess could potentially be harmful, especially is applied through a nasal applicator. As with all supplemental regimens, balance is the key to recovery.
Two Other Remedies for Loss of Smell
Studies show a significant B12 and vitamin D deficiencies in persons with Parkinsons symptoms. Both are also implicated with an impaired ability to smell.
Summary
Eager to smell better? Talk with your doctor about treating deficiencies of zinc, B12 and Vitamin D by taking supplements or eating foods that contain them,
I predict you will be pleased with the outcome. After all, smell is one of the magical wonders of life.
Berberine is a natural compound found in the roots, stems, and the bark of various plants such as European barberry, goldenseal, Oregon grape, and tree turmeric. It also facilitates the production in the body of the AMPK enzyme found to be deficient in individuals confronting neurological challenges.
Available as an over the counter supplement in companies such as Life Extension for a modest cost.
Recent studies report a strong connection between insulin resistance and Parkinson’s symptoms. Berberine supports healthy blood sugar metabolism which is another reason why researchers are suggesting its beneficial effects for Parkinsons and Alzheimers.
Below are listed abstracts of recent studies that recommend Berberine as a treatment for neurological conditions.
Neurotox Res. 2022 Aug;40(4):1096-1102. Can Berberine Serve as a New Therapy for Parkinson’s Disease?
Abstract
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic neurodegeneration and deposition of alpha-synuclein. Mechanisms associated with PD etiology include oxidative stress, apoptosis, autophagy, and abnormalities in neurotransmission, to name a few. Drugs used to treat PD have shown significant limitations in their efficacy.
Recent focus has been placed on the potential of active plant ingredients as alternative, complementary, and efficient treatments. Berberine is an isoquinoline alkaloid that has shown promise as a pharmacological treatment in PD, given its ability to modulate several molecular pathway associated with the disease. Here, we review contemporary knowledge supporting the need to further characterize berberine as a potential treatment for PD.
Int J Clin Pharmacol Ther. 2025 Sep;63(9):432-438. Anti-neurodegenerative treatment in Alzheimer’s disease: Multifaceted mechanisms of action of berberine
Abstract
Background: Berberine, a traditional Chinese medicine, has demonstrated significant therapeutic influences in treating diabetes, obesity, and diarrhea, among other conditions. It has exhibited potential therapeutic benefits for various neurodegenerative diseases, namely, Alzheimer’s disease (AD), Huntington’s disease (HD), and Parkinson’s disease (PD).
Aims: This study aims to elucidate the mechanism behind berberine pharmacological action in treating AD.
Materials and methods: We search the articles published in PubMed and CNKI and summarize the mechanism of berberine in AD.
Results: In recent years, as research into the pharmacology of berberine has deepened, researchers have discovered its strong neuroprotective properties. The ability of berberine to enhance cognitive function is thought to result from inhibiting the spread of AD-related proteins, reducing oxidative stress and inflammation, increasing choline levels, and regulating autophagy.
Conclusion: This review explores the latest research on berberine in AD, suggesting that berberine and its analogs may offer a promising new approach to treating the condition.
Front Pharmacol. 2022 May 20:13:845591. Berberine: A Promising Treatment for Neurodegenerative Diseases
Abstract
Berberine, as a natural alkaloid compound, is characterized by a diversity of pharmacological effects. In recent years, many researches focused on the role of berberine in central nervous system diseases. Among them, the effect of berberine on neurodegenerative diseases has received widespread attention, for example Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and so on.
Recent evidence suggests that berberine inhibits the production of neuroinflammation, oxidative, and endoplasmic reticulum stress. These effects can further reduce neuron damage and apoptosis.
Chem Biodivers. 2025 Aug;22(8):e202500170. Unraveling Berberine’s Molecular Mechanisms in Neuroprotection Against Neurodegeneration
Abstract
Neurodegenerative diseases (NDs) exhibit significant global public health challenges due to the lack of effective treatments. Berberine (BBR), a natural alkaloid compound in various plants, has been recognized for its potential neuroprotective properties.
This review explores the current understanding of BBR’s mechanisms of action and its therapeutic potential in preventing and treating NDs such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease.
BBR’s neuroprotective properties are attributed to its multifaceted actions, including anti-inflammatory, antioxidant, antiapoptotic, and neurotrophic effects. In addition, BBR can influence many signaling pathways involved in neurodegeneration, including AMP-activated protein kinase (AMPK), nuclear factor erythroid 2-related factor 2, and brain-derived neurotrophic factor pathways. Furthermore, BBR targets vital signaling pathways, including AMPK, PI3K/Akt, and MAPK, which are essential for developing NDs.
In addition, BBR’s efficacy in reducing neurodegenerative pathology and improving cognitive function has been demonstrated through preclinical studies using cellular and animal models. Clinical trials demonstrating BBR’s therapeutic potential in NDs have yielded promising results.
Inflammopharmacology. 2025 Apr;33(4):2129-2150. Neuroprotective efficacy of berberine and caffeine against rotenone-induced neuroinflammatory and oxidative disturbances associated with Parkinson’s disease via inhibiting ?-synuclein aggregation and boosting dopamine release
Abstract
Parkinson’s disease (PD) is characterized by motor impairment, glial-mediated inflammation, redox imbalance, and synuclein aggregation. Conventional therapies relieve early PD symptoms, but they do not repair dopaminergic neurons.
Berberine (BBR) and caffeine (CAF), both natural alkaloids, exhibited neuroprotective effects in many neurodegenerative disorders. Consequently, we hypothesized that the combination of BBR and CAF therapies would offer protection against PD-related impairments in the rotenone (ROT)-induced rat model when compared to the commercial drug, metformin (MTF).
Results showed that the combined administration of BBR (25 mg/kg/day) and CAF (2.5 mg/kg/day) for four weeks prevented motor deficits, weight reduction, dopamine (DA) depletion, and monoamine oxidase (MAO) activity in ROT-induced rats in comparison with monotherapy of BBR and CAF along with MTF. This combination produced a notable neuroprotective effect by reducing tumor necrosis factor (TNF)-? and interleukin-16 (IL-6) in midbrain of rats. BBR and CAF combinations markedly normalized tyrosine hydroxylase (TH) levels and decreased total ?-syn and ?-syn-pser129 aggregation and increased protein phosphatase 2A (PP2A) levels.
Histological analysis indicated that damaged neurons exhibited significant amelioration with the co-administration of BBR and CAF. The molecular docking results indicated that both BBR and CAF had notable binding affinity for the protein pocket surrounding the ?-syn, PP2A, and TH in comparison to MTF. They are predicted to serve as effective inhibitors of enzyme-mediated phosphorylation of ?-syn-pser129.
Conclusively, combined BBR and CAF administration presents a novel strategy for neuroprotection by blocking the initial events in PD incidence, demonstrating considerable anti-oxidative and anti-inflammatory benefits relative to MTF.
Now here is something interesting to do, especially if you ever wondered what your voice says about you. It is called Nano voice and is available on the Sound Health Portal for free. Here is the link to get a free analysis of your voice.
Once you land on the Nano Voice page above, click Start. Then, talk in a normal voice without pauses for 90 seconds. An analysis of the frequencies emitted by your voice will be instantly provided.
Once you generate your first overview report, you can restart Nano voice and talk a second time for 90 seconds to generate a follow-up report. I talked for 90 seconds three times back to back. The three reports of my personality were all very similar. I must report they also described me to a tea.
Why bother?
It is free
It takes only 5 minutes
The instant report that is generated is fascinating
This short activity will convince you to take analysis of voice profiles seriously. Healing through sound (and light) is the medicine of the future
You likely know nothing about AMPK signaling deficiencies or their connection to the following Parkinsons symptoms:
Muscle Cramps (hands, feet, trunk)
Muscle loss
Memory loss
Waking up at 2 am and unable to get back to sleep
Restless legs
Adrenal Exhaustion
Thinning hair
Low energy
Sharry Edwards fromSound Health Options has recently discovered significant AMPK deficiencies for persons who experience symptoms of Parkinsons. This is truly a ground breaking discovery that has profound implications for persons confronting neurological symptoms.
What is AMPK?
The AMPK enzyme is naturally made by the body in the brain, liver, pancreas and other organs. It does not exist as a supplement. You can not buy AMPK like you can buy a vitamin (like vitamin C). You can purchase a product containing herbs that facilitate the production of AMPK by the body.
The AMPK enzyme is the master regular of glucose metabolism and is now recognized as an enzyme that reverses aging.
There is a compelling body of recent research on Parkinsons that connects pre-diabetic conditions to its symptoms. People with Parkinsons are found to have insulin resistance. The AMPK stabilizes sugar levels and thus promises to be a valuable, but little known therapeutic remedy to offer relief from troublesome symptoms.
Four Options to Reverse AMPK Signaling Deficiencies
Stop drinking diet sodas or ingesting any product that contains aspartame which impairs the natural production of AMPK by the body.
Begin taking an AMPK supplement available on Life Extension which contains ingredients that support and facilitate the natural production of AMPK in the body.
Begin taking the supplement Berberine which also supports the production of AMPK by the body and helps to stabilize sugar levels.
Contact Sound Health Options (www.soundhealthoptions.com) to participate in their ongoing study to infuse the AMPK enzyme with the sound of its equivalent frequency otherwise known as Frequency Medicine.
However you or your family member decides to proceed, please let me know of your experience. This is one of those ground breaking discoveries that will become common knowledge ten years from now. You heard about it from Parkinsons Recovery today.
How do you believe alternative therapy paves a path to recovery and who do you think is most likely to succeed choosing natural therapies
How have you personally witnessed advancement in sound therapy as a healing modality for conditions in the body?
Have you witnessed miracles in your line of work leading people on their path to whole body healing?
Tell us about the results of the original research you participated in with vibroacoustic therapy
Do you believe there is a cure for Parkinsons?
I heard you’ve expanded to using scalar energy for daily energy shift, give us a lay person’s synopsis and what people should look for to find it in their area.
What are you plans for the near future to expand awareness about these leading edge technologies?
Robert Rodgers PhD Founder 2004 Parkinsons Recovery https://www.parkinsonsrecovery.com
Twenty years of research and interviews with persons diagnosed with Parkinsons have unearthed a rich set of natural therapies to reverse symptoms.
This 2025 book includes the therapies and methods that have enabled others with Parkinsons to celebrate a successful journey down the road to recovery.
I am very hesitant to provide a listing of all the treatments and therapies people have told me help to relieve their tremors. Why? After all – putting out such as list would impress everyone, wouldn’t? This guy has great suggestions people would say. Well – maybe.
I do offer suggestions in my books by way of reference, but the problem I have with providing specifics is that I know little about your actual situation. The question itself hits up against the strategy of masking symptoms rather than identifying the root cause.
When there are tremors – as in your case – your body is sending you a strong message that something is seriously out of balance. Perhaps the imbalance involves exposure to toxins. Perhaps it involves a past trauma that is unresolved. Perhaps it involves living a stressful life that offers your body little relief from a continuous adrenaline rush. Perhaps it is due to an insufficiency of certain substances the body needs to create energy.
There is a long list of possible causes.
I think the better questions to ask first are:
Why is my body sending me this strong signal?
What is causing my body to react as it is reacting now?
There are indeed a long list of possible answers to these questions. How do you find the answers to these questions?
A variety of assessments are available to you that can provide rich information about any and all imbalances in your body. These include (among others) bioenergetic testing, saliva tests, voice analysis, hair analysis to ascertain the presence of toxins and a wide variety of standard medical tests.
Health care practitioners have creative ways to ascertain the root cause using muscle testing.
In summary, I would say in response to your question that yes – it is certainly possible to mask a tremor with a wide variety of approaches including prescription medications, natural herbs and exercise. With most such treatments (other than exercise) more and more dosage is needed over time to get the same effect. You ultimately wind up creating more problems for yourself as the imbalances become more pronounced.
Why not ask a different set of questions here?
What is the underlying cause here?
What is my body telling me in the moment?
Once you figure out the answer to these questions you can find a treatment or therapy that will address the cause. With this approach masking the tremor becomes irrelevant.
I have developed an online course called tame tremors which presents classes on dozens of natural treatments. Once you identify the likely cause, you have a rich source option to choose from.
Hi Robert: I want to report a win that was obtained based on your video on Trudose with Robin. It doesn’t actually have to do with Trudose but Mucuna Pruriens.
My mother is in her 80s and late stage PD. The other day she was depressed and crying due to her state and inability to move. I want more of a long term solution for her but I needed to do something to help and I remembered Robin’s comments on the book on Mucuna Pruriens so I got the kindle version and skimmed it to get the necessary info to dose it which is pretty basic: Reduce Sinamet and replace with an equal dose of equivalent mucuna.
We initially went from 100/50 Sinemet and halved it and added the Now brand Mucuna Pruriens which contains 60mg L-dopa so end result was 50/25 plus 60mg L-dopa from the Now extract. That worked great for one the first day and not great for a couple so we went to a full tablet 100/50 plus one capsule first thing in the morning then to 50/25 and one capsule the rest of the day. This has worked well for 3 or 4 days in a row so I don’t think it’s a fluke now. FYI she is also on 2mg LDN.
As for me I am still not taking any medication however, it is challenging for me to reduce the tremors. I have reduced my lead levels from 74.4 to 4.4 over 6 months where 3.5 is normal so huge progress. Based on lab testing done with Dr. Lisa (one of John Coleman’s proteges) my glyphosate is in the 99th percentile so very very high. John and Lisa will assess my case based on the toxin profile and organic acids as well as the big picture and I should meet with Lisa on the 6th.
While I have been detoxing I also have been heavily pursuing a biomechanical approach including facial myofascial (may do a tongue tie release this month) and occlusal therapy, chiropractic to include nasal cranial release, Functional Patterns biomechanical approach, and John Pepper’s walking routine. I’m doing Vielight MIP, PEMF and other stuff as well. Trudose is still on my shortlist however I want to get my toxin levels down to a reasonable level. I found a place a couple hours away that does it. Thanks, John
Robert Rodgers PhD Founder 2004 Parkinsons Recovery https://www.parkinsonsrecovery.com
The link to a 10 minute movie clip listed below previews Allen Babbitt’s method to take control of tremors. Instead of fighting them, he takes control of them. How could this be?
Other Parkinsons photographers find ways to suppress their tremors when taking photographs. Not Allen. When shooting photographs, his tremors are an unexpected advantage. The images are remarkable because – of all things – tremors shake his camera which is his special method to take control of tremors.
The cover of my best selling book Road to Recovery from Parkinsonsis a photograph taken by photographer Allen Babbitt. I loved the image that is featured on the cover. Tremors make his photos truly unique and a special treat for those who also happen to be diagnosed with Parkinson’s disease. For Allen, tremors were not a liability. They were an asset.
The best 10 minutes of your day today will be spent watching the following video about Allen, his Parkinsons, his photography and his recommendation for others traveling down the road to recovery. Visit the link below to watch.
In the video Allan demonstrates a trick he discovered that calms his tremors when he walks. He tosses a ball back and forth from one hand to the other and presto. Tremors are instantly quieted.
I just learned that Allan died a few months ago and wanted to pay tribute to an amazing individual and a gifted photographer who has been an inspiration to many including me!
Two ancient practices show promise for Parkinsons: Qigong and Tai Chi. Two individuals in particular have experienced profound symptom relief . One embraced Qigong. The other embraced Tai Chi. Both methods quiet the mind and reduce day to day stresses that are problematic for persons diagnosed with Parkinson’s Disease.
The first approach which proved successful for Bianca Molle is Qigong. The second which proved successful for Daniel Loney is Tai chi. Each method originated in the East many, many years ago. Qigong and Tai Chi are both tried and true methods that have obviousy survived the test of time.
Some of the therapies that people place the most confidence in have emerged within only the past few decades and have not yet passed the acid test of time. In my “book” of successful therapies, continuous use of a therapy for centuries on end counts for something. When people across the continents practice methods like Qigong and Tai Chi for hundreds of years they must be worthwhile, eh?
I am personally dazzled at the success these two individuals have manifested. They are true pioneers of natural methods that are helping more and more people across the globe reverse Parkinson’s symptoms. Techniques of Qigong and Tai Chi obviously differ but the end result is similar. They both help to bring the delicate balance of hormones that are critical to neurological health back to their natural state.
QiGong
You can obtain more information about my interview with Bianca Molle who finds Qigong to be the therapy that worked for her by visiting:
Daniel Loney has clearly found profound relief from his symptoms through a systematic practice of Tai Chi. He is now an active proponent of Tai Chi. He says it has helped him and other people with Parkinson’s Disease enormously.
You can discover more information about my interview with Daniel Loney by visiting the book website:
These Two Ancient Practices Show Promise for Parkinsons as demonstrated by these two remarkable individuals who have been traveling down the road to recovery.
People Who Discovered Natural Treatments for Parkinson’s Disease Tell Stories of Their Recovery
Pioneers of Recovery is a 364 page book that covers natural therapies for Parkinsons recommended by health care professionals and persons with Parkinson’s who discuss the ways they reversed their symptoms.
Each person has a unique story, but each story is packed with hope and promise for a better tomorrow. Of course, recovery can be slow and frustrating, but the stories reveal an indisputable truth. A little experimentation and courage goes a long way toward fitting pieces of the puzzle of recovery together.
People with Parkinsons are discovering effective ways to get good relief from their symptoms with natural methods. Some people are symptom free today. There is hope, especially when you see what smart things people with Parkinson’s are doing for themselves to get well.
About the Interviews with Pioneers
What follows the questions I asked of each pioneer. Each person I interviewed read and edited the transcript of their interview. The interviews capture what the person really said and meant, not my interpretation of what they said or meant.
Andrew Bentley – Herbalist
Andrew Bentley Herbalist
What does a herbalist do for people?
What herbs in your past experience are helpful for people who have central nervous system challenges?
If a person came in and had a dominate tremor, that would inform a certain set of herbs or maybe just one dominate herb versus if someone came in with a dominate symptom of pain and rigidity, that would inform a different recommendation of herbs?
Many people ask me a question about excessive salivation. Is there anything you would suggest as a possibility in the herbal area for that?
What would be recommendations for a person who presents depression as a primary symptom?
Could you talk about your experience with people who have the symptoms of Parkinsons and how these herbs have helped them?
It sounds like for the people with Parkinson’s that you have seen the results are indeed encouraging. People are seeing relief from their symptoms. You offer hope that there are people who have become virtually symptom free – maybe not totally – but virtually symptom free. Do I understand that correctly? Is that what you said?
One specific herb that I do not think you have mentioned (and what many people are interested in is called Mucuna. Many people have been acquiring that from India as a dopamine supplement. Do you prescribe Mucuna for your patients?
Carl Buchheit Neuro-Linguistic Programming (NLP)
Can NLP be useful to persons who have the symptoms of Parkinson’s?
One of the common symptoms of Parkinson’s is anxiety. If a person were to focus on a specific event or events that create the anxiety, then would it be possible working with an NLP therapist to find quick relief from that anxiety?
You mentioned some of the misinformation on the internet about NLP. Do you have other books or tapes or CD’s that you would recommend people might look at to find out more about NLP?
There are many people that believe once they are diagnosed with Parkinson’s they are always going to get worse. From my understanding of what you have said, you have worked with individuals with Parkinson’s who have gotten better. Is that correct?
Chris Bliss Comedian, Juggler
When you are juggling and when you are in that place of perfect balance and harmony, hat does it feel like?
In your shows you do both the comedy and juggling. As I understand it, what you are saying is that many times that place of perfect harmony and balance is actually present when you are doing both, not just when you are juggling?
For people with the symptoms of Parkinsons fear and tress are huge issues. When fear and stress are up, symptoms flare. Do you ever feel fearful or stress when you are juggling? How do you get yourself out of being in fear when fear rolls in while you are performing, if it ever does?
People with Parkinsons who are finding ways to feel better tell me that there are certain things that help them feel more in balance. I want to ask you if you do these things.
Many who have the symptoms of Parkinson’s tell me they are very careful about making sure they are properly hydrated, that they drink enough water. Is that anything that is conscious for you?
People also tell me they have various ways they relieve stress. Everybody faces stress every day. One of the ways to release stress is humor. Is humor one of the biggest ways you relieve your own stress?
A number of people have told me that they have had great relief from their symptoms because they have such strong support systems and support networks. Yet, you are often traveling. You are all over the place. Do you have a strong social network or support system for yourself?
What practical suggestions do you have for people who are trying to live their lives in that very same space you are in when you are juggling?
Jean Oswald, R.N., CCA – Aromatherapist
When I use the term “essential oils” what is that exactly? What is an essential oil?
How would I know what type of essential oil will help me? For example, if my symptoms are tremors and rigidity, are there specific essential oils that can help offer me some relief from my symptoms?
Has there been research to evaluate the impact of essential oils?
What if an individual has problems with muscle rigidity and it is very difficult for them to move with ease. What is an essential oil that might help relieve that particular symptom?
How about the problem of tremors? What essential oils might be recommended to relieve that symptom?
A problem some people have is with excessive salivation. Are there any essential oils that come to mind specifically for that symptom?
How about insomnia?
Many people I interview talk quite extensively about stress and how that affects them. When they are under extreme stress their symptoms flare up. Can essential oils address the problems that stress creates?
There are some reports that pathogens and bacterial infections confound the symptoms of Parkinson’s. Do essential oils have the potential to address those pathogens?
Lisa Brown Physical Therapist
If I am a person who has had these challenges, when I go to you is it a question of your moving my arms and legs around so that they are more flexible or do you work with me in terms of helping me how to walk?
A lot of people you see have had difficulty with falls or other problems. Is there any reason why a person who is first diagnosed with the symptoms of Parkinson’s should come to you in the very beginning?
When a person comes to see you is it likely that they will get a relief from symptoms and feel better or are they going to feel worse?
You have extensive experience working with persons who have Parkinson’s. Do you have an exercise protocol that you give to people that you recommend everybody does or is the work you do very specific to the person’s needs?
What would you say is the most important thing for persons with Parkinson’s to know about movement and about flexibility? What would you want them to know would be most important?
Steve Fenwick, Ph.D. – Psychologist
What often happens then is that when a person comes to see you, they will come with a dream and you will help them sort through what that dream means?
Let’s say a person with the symptoms of Parkinson’s is shaking or tremoring. What might be an interpretation that is possible of the shaking or tremoring in the context of the person’s entire life?
Let’s say I had Parkinson’s and I came to you. We begin to work together and the approach is to help me exaggerate my symptoms which is tremoring of my hand. Am I going to have certain thoughts that I didn’t expect? Will I have certain feelings that I didn’t expect or revelations? What is likely to happen?
How might people with Parkinson’s be helped if they do Process Work? Is it going to be connected somehow with being able to get some relief from their symptoms and feeling better?
John Coleman, ND Naturopath
How did you come to the realization you could get better when all indications were that you would get worse?
There is so much information out there about what is supposed to help – vitamins, supplements, body therapies, etc. etc. How did you go about deciding what to try in terms of therapies, supplements, doctors, etc.?
Which therapies/approaches did not work for you?
What has helped you get the most relief from your own symptoms?
Is there anything in particular that you recommend for the symptoms of:
Inability to sleep
Pain
Constipation
Tremors
What was recovery like for you?
What about your patients… what has their experience been like?
Among your patients with Parkinson’s, how many are getting relief from their symptoms? How many have been able to see full relief from their symptoms?
Does a person have to make any lifestyle changes to recover?
It took you three and a half years to recover. That is a long time to sustain hope. How did you do it?
How can I reduce or manage my rigidity, spasms and burning sensations?
When should we start taking medication?
Could you discuss the approaches using the Emotional Freedom Technique for my Parkinson’s condition and your opinion of the value of the technique?
How long did it take you see substantial symptom relief? How long did it take to become symptom free?
Max
Can you talk a little bit about the detoxing work that you have done and the Ayurvedic work?
Is it hard to stick to a diet?
Your experience varies from day to day? Every day is a new experience?
You notice a very strong, direct relationship between stress and the symptoms?
What types of things do you do other than all the meds to be able to release some of that stress that you’re under?
If there is one thing you would say about what’s helped you the most to be able to feel better and get relief from your symptoms, what would it be? What would you tell people they really should do, whatever it may be?
Sandy
What are some of the struggles you have had with Parkinson’s? Are you taking traditional medications?
Do you take other supplements or herbs or vitamins?
What are some of the things you do to help you feel better?
You have really been able to continue doing all the things you have always done without much interruption?
I am sure there are modalities, therapies and approaches that you have tried since you have had Parkinson’s that really did not offer much help. Could you talk about those?
What about other approaches, therapies and modalities that you have tried that have offered you some relief and have helped you feel better?
When you say they tested you for lead and mercury, was this with saliva or blood or hair samples or …? How did the test actually work?
Many believe once you begin to have the symptoms of Parkinson’s you are always going to get worse and feel worse. From what you have described it sounds like that really has not happened for you. Is that right?
When tension comes up what happens when you choose to exercise rather than relax?
Do the symptoms get better when you exercise?
Stan
We are all interested to know what you have tried, what has worked and what has not. Could you talk a bit about what your experience has been?
When you talk about meditation could you possibly say a little more about specifically what type of meditative approach works best for you?
Do you notice when you do this meditative technique that there is a relief in symptoms?
What other approaches or natural therapy do you use that you find gives you relief of your symptoms?
Are there any dietary concerns that you have or that you would like other people to know about that seem to make a difference?
So what about exercise? Do you notice any connection between activity, exercise and feeling better?
What would you want to say to someone who has just heard the news that they have Parkinson’s?
Over the course of the period that you have had the symptoms, it sounds like what you have been able to do is to find a number of ways to get relief as those symptoms begin to flare up?
Mary
What you have been doing to get relief from your symptoms?
What about craniosacral work?
You have done so many therapies and tried so many things. Some of them haven’t helped and some of them have. Are you getting better?
Is there anything that you would want to be sure and say to a person who is just been diagnosed with Parkinson’s?
About how much time everyday or every week do you spend on your exercise program?
You definitely notice a difference? When you exercise you feel better and when you don’t exercise you feel worse?
Nathan
Tell us who you are and what your story is in terms of having had Parkinson’s and being able to recover.
You mentioned that a lot of the work that you were doing was challenging. After you were able to recover, were you able to go back full steam into doing work and other kind of activities?
What would you say to somebody who has just been diagnosed with Parkinson’s?
Are you in contact with or do you know many other people whose story is similar to yours – people who had Parkinson and have been able to get relief from their symptoms?
Could you summarize for people, from just your own experience and observations of others, what is it that happens to others who do not recover – who are not able to feel better?
You’ve also described your own recovery is not exactly a smooth ride up. Are there some rocky spots on the path to recovery?
What do you have to do to help your body detox?
Carl
What generally did the doctors recommend would be a good path to pursue?
Can you talk a bit about exactly what you’re doing now? Are you still doing the craniosacral therapy?
Are you taking supplements of one kind or another?
Are there any dietary rules that you have for yourself that are important?
What would you say to anyone who’s just discovered that they’ve been diagnosed with Parkinson’s? What kind of help, insight or comments would you want them to hear?
Is there anything that you’ve regretted doing? Or trying?
Taube
So, you’ve responded by getting a lot of good medical advice and attention. What other kinds of things have you done in response to this medical challenge?
What do you suppose might have been the contributing factors that created the symptoms for you?
You’re out there exploring and experimenting and have quite fascinating experiences. For a person that might first be discovering that they have the symptoms of Parkinson’s, what would you want to say to them? What advice would you give to them?
When you say you do eat well, could you provide any specifics on that? I mean, steak, mashed potatoes, french fries, milkshakes? What is it that you like to eat? What do you try to avoid?
Did you get some relief from your symptoms after attending Hypocrates? Have you been able to keep up with the dietary regimen?
When you are eating food that your body needs and loves you feel better, so that is a motivator in itself?
Summary
I invite you to select some of the approaches to recovery previewed in Pioneers of Recovery to launch your own personal program of recovery. There are many genuinely rich and useful approaches to recovery. Once you discover options that work the magic for you you have launched a successful journey down the road to recovery.
Robert Rodgers PhD Founder 2004 Parkinsons Recovery https://www.parkinsonsrecovery.com Olympia, Washington robert@parkinsonsrecovery.com
Insulin resistance correlated with Parkinson’s symptoms: One of the most ground breaking research discoveries of the past decade ….
Are you tired all the time. Do you usually have little energy?
The breakdown of glucose synthesis may well be the reason. Metabolically, insulin receptors play a key role in the regulation of glucose homeostasis, Insulin signaling controls access to blood glucose in body cells.
Do you typically feel better in the morning before you have had something to eat? This is a clue that you may be susceptible to insulin resistance. Fasting over night means that is a 12 hour or more period you have not eaten anything. This is the condition needed by the body for the liver to manufacture ketones. Before eating anything in the morning. your brain is being efficiently fueled by ketones rather than glucose which is the by product of eating anything.
Epidemiological evidence and experimental data support the interaction between Parkinson’s and diabetes. Treatments for diabetes show promising neuro-protective results in PD patients for both diabetic and non-diabetic patients, Therefore, the role of anti-diabetic treatments for Parkinson’s patients offers a promising therapeutic approach
Ask your self – why are so many persons diagnosed with neurological conditions so thin? A logical reason is that when they eat, their symptoms worsen, so they do not eat regularly
Studies that find the connection between insulin resistance and Parkinson’s symptoms
Mov Disord. 2022 Aug;37(8):1612-1623. The Impact of Type 2 Diabetes in Parkinson’s Disease. Dilan Athauda, James Evans, Anna Wernick, Gurvir Virdi, Minee L Choi, Michael Lawton, Nirosen Vijiaratnam, Christine Girges, Yoav Ben-Shlomo, Khalida Ismail, Huw Morris, Donald Grosset, Thomas Foltynie, Sonia Gandhi
Abstract
Background: Type 2 diabetes (T2DM) is an established risk factor for developing Parkinson’s disease (PD), but its effect on disease progression is not well understood.
Objective: The aim of this study was to investigate the influence of T2DM on aspects of disease progression in PD.
Methods: We analyzed data from the Tracking Parkinson’s study to examine the effects of comorbid T2DM on PD progression and quality of life by comparing symptom severity scores assessing a range of motor and nonmotor symptoms.
Results: We identified 167 (8.7%) patients with PD and T2DM (PD + T2DM) and 1763 (91.3%) patients with PD without T2DM (PD). After controlling for confounders, patients with Type 2 Diabetes had more severe motor symptoms, as assessed by Movement Disorder Society Unified Parkinson’s Disease Rating Scale, Part III (25.8 [0.9] vs. 22.5 [0.3] P = 0.002), and nonmotor symptoms, as assessed by Non-Motor Symptoms Scale total (38.4 [2.5] vs. 31.8 [0.7] P < 0.001), and were significantly more likely to report loss of independence (odds ratio, 2.08; 95% confidence interval [CI]: 1.34-3.25; P = 0.001) and depression (odds ratio, 1.62; CI: 1.10-2.39; P = 0.015). Furthermore, over time, patients with T2DM had significantly faster motor symptom progression (P = 0.012), developed worse mood symptoms (P = 0.041), and were more likely to develop substantial gait impairment (hazard ratio, 1.55; CI: 1.07-2.23; P = 0.020) and mild cognitive impairment (hazard ratio, 1.7; CI: 1.24-2.51; P = 0.002) compared with the PD group.
Conclusions: In the largest study to date, T2DM is associated with faster disease progression in Parkinson’s, highlighting an interaction between these two diseases. Because it is a potentially modifiable metabolic state, with multiple peripheral and central targets for intervention, it may represent a target for alleviating parkinsonian symptoms and slowing progression to disability and dementia.
Mov Disord. 2021 Jun;36(6):1420-1429. Type 2 Diabetes as a Determinant of Parkinson’s Disease Risk and Progression. Harneek Chohan, Konstantin Senkevich, Radhika K Patel, Jonathan P Bestwick, Benjamin M Jacobs, Sara Bandres Ciga, Ziv Gan-Or, Alastair J Noyce
Abstract
Background: Type 2 diabetes (T2DM) and Parkinson’s disease (PD) are prevalent diseases that affect an aging population. Previous systematic reviews and meta-analyses have explored the relationship between diabetes and the risk of PD, but the results have been conflicting.
Objective: The objective was to investigate T2DM as a determinant of PD through a meta-analysis of observational and genetic summary data.
Methods: A systematic review and meta-analysis of observational studies was undertaken by searching 6 databases. We selected the highest-quality studies investigating the association of T2DM with PD risk and progression. We then used Mendelian randomization (MR) to investigate the causal effects of genetic liability toward T2DM on PD risk and progression, using summary data derived from genome-wide association studies.
Results: In the observational part of the study, pooled effect estimates showed that T2DM was associated with an increased risk of PD (odds ratio [OR] 1.21, 95% confidence interval [CI] 1.07-1.36), and there was some evidence that T2DM was associated with faster progression of motor symptoms (standardized mean difference [SMD] 0.55, 95% CI 0.39-0.72) and cognitive decline (SMD -0.92, 95% CI -1.50 to -0.34). Using MR, we found supportive evidence for a causal effect of diabetes on PD risk (inverse-variance weighted method [IVW] OR 1.08, 95% CI 1.02-1.14; P = 0.010) and some evidence of an effect on motor progression (IVW OR 1.10, 95% CI 1.01-1.20; P = 0.032) but not on cognitive progression.
Conclusions: Using meta-analyses of traditional observational studies and genetic data, we observed convincing evidence for an effect of T2DM on PD risk and new evidence to support a role in PD progression.
J Parkinsons Dis. 2020;10(3):775-789. The Association Between Type 2 Diabetes Mellitus and Parkinson’s Disease. Julia L Y Cheong, Eduardo de Pablo-Fernandez, Thomas Foltynie Alastair J Noyce
Abstract
In recent years, an emerging body of evidence has forged links between Parkinson’s disease (PD) and type 2 diabetes mellitus (T2DM). In observational studies, those with T2DM appear to be at increased risk of developing PD, as well as experiencing faster progression and a more severe phenotype of PD, with the effects being potentially mediated by several common cellular pathways. The insulin signalling pathway, for example, may be responsible for neurodegeneration via insulin dysregulation, aggregation of amyloids, neuroinflammation, mitochondrial dysfunction and altered synaptic plasticity. In light of these potential shared disease mechanisms, clinical trials are now investigating the use of established diabetes drugs targeting insulin resistance in the management of PD.
Pioneers of Recovery offer rich insights into what it takes to celebrate relief from Parkinson’s symptoms. The ten individuals featured in Pioneers of Recovery found different ways to reverse their Parkinson’s symptoms.
Pioneers of Recovery print book is available on Amazon here: Pioneers of Recovery
Your download is not automated. It usually takes a few hours to receive it in your email or the next day it you order during the evening.
Below are minute long clips from the Pioneers of Recovery who offer rich insights into their recovery process. Causes of their symptoms varied considerably. Their approaches to recovery were all very different.
Bianca on Recovery
Cheryl on Recovery
Daniel on Recovery
Gord on Recovery
Howard on Recovery
Karl on Recovery
Lexie on Recovery
Lydia on Recovery
Marian on Recovery
Discover the details of how each pioneer reversed their symptoms which are documented in Pioneers of Recovery available on Amazon.
Or better yet, listen to my interviews with each of the pioneers. You will be inspired by the many options that make recovery possible
Studies find that Astaxanthin for Parkinsons has potent anti-inflammatory effects. and is recommended by researchers as a treatment for Parkinsons. Abstracts of two studies (among over 100 studies) are included below.
As with any antioxidant, many outlets for Astaxanthin are available. Some are reputable. Many are not.
I recommend one source in particular which is available from Valasta (https://www.valasta.net). Their formulation was inspired by a fascinating question that molecular biologist Sam Sheppard asked: What animals do not get cancer? We all know dogs and cats get cancer. Which ones do not?
Sam’s research revealed five animals in particular never get cancer:
Elephants
Salmon
Pink Flamingos
Sharks
Naked Mole Rats
Now that is an interesting list of animals, eh? Sam then asked the critical question: What does this motley group of animals have in common? The Answer: They all had a robust supply of Astaxanthin.
This is basic research at its best. Clearly there are many anti-oxidant and anti-inflammatory options that have been determined useful as treatments for Parkinsons, but Astaxanthin for Parkinsons has significantly increased potency and is well worth including in your program of recovery.
For more information about Sam Sheppard and his journey down the road to recovery visit https://www.valasta.net
Antioxidants (Basel). 2025 Jun 12;14(6):715. Astaxanthin: A Compound in the Prevention of Chronic Diseases and as a Potential Adjuvant Treatment Agen
Abstract
Astaxanthin (AST) is a fat-soluble carotenoid antioxidant. AST exhibits multiple protective mechanisms, including its antioxidant, anti-inflammatory, immunomodulatory, anti-apoptotic, nervous system-protective, anti-tumor, and anti-fibrotic effects. These effects make it a promising compound for the prevention of chronic diseases.
AST can protect the nervous system against neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. It also protects the liver and helps reduce the risk of chronic kidney disease. Additionally, it improves cardiovascular health and has anti-diabetic properties.
This review aims to provide an updated overview covering the protective effects of AST against various chronic diseases, including its antioxidant, anti-inflammatory, and anti-apoptotic effects. We also discuss the strategies used for improving astaxanthin bioavailability and its potential as an adjuvant therapeutic agent.
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Pharmacol Res. 2021 Apr:166:105479. Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials
Abstract
Astaxanthin is a natural C40 carotenoid with numerous reported biological functions, most of them associated with its antioxidant and anti-inflammatory activity, standing out from other antioxidants as it has shown the highest oxygen radical absorbance capacity (ORAC), 100-500 times higher than ?-tocopherol and a 10 times higher free radical inhibitory activity than related antioxidants (?-tocopherol, ?-carotene, ? -carotene, lutein and lycopene).
In vitro and in vivo studies have associated astaxanthin’s unique molecular features with several health benefits, including neuroprotective, cardioprotective and antitumoral properties, suggesting its therapeutic potential for the prevention or co-treatment of dementia, Alzheimer, Parkinson, cardiovascular diseases and cancer.
Benefits on skin and eye health promotion have also been reported, highlighting its potential for the prevention of skin photo-aging and the treatment of eye diseases like glaucoma, cataracts and uveitis.
Parkinsons Recovery is dedicated to identifying promising new therapies that offer the promise of reversing symptoms of Parkinson’s disease. One such
therapy, High-Dose Thiamine, was discussed on Parkinsons Recovery Radio during an interview with Italian neurologist Antonio Constantini MD. He prescribed High Dose Thiamine as a treatment for his Parkinson’s patients with good success. Click on the pointer to hear the replay.
Parkinsons disease is a systemic disease with motor and non-motor deficits. In July 2011, Dr. Costantini treated a 47-year-old man affected by spinocerebellar ataxia type 2 (SCA2). In this patient, fatigue as well as motor symptoms improved after parenteral high doses of thiamine (also this was our proprietary research).
He formulated the hypothesis that in some inherited and degenerative diseases of the nervous system, the pathogenesis of the symptoms could be linked to a focal thiamine deficiency due to a dysfunction of the circulation of thiamine in the intracellular space or to structural enzymatic abnormalities. He speculated this dysfunction could be responsive to high-dose thiamine. Parkinson’s disease has also been related to mutations associated with SCA2. Applying the same approach to patients with Parkinson’s symptoms the observed results were nothing short of startling and never previously described in literature.
I have included my full interview with Bill Curtis on Parkinsons Recovery Radio who discusses ketone esters for Parkinsons. He provides a remarkable summary of his customized treatment protocol involving ketones, fasting and exercise which has quieted his symptoms for many years now.
You having to take more and more medications to achieve relief? Bill has been taking five (5) prescription medications for many years with no requirement to increase dosages.
In summary I promise you will not regret taking 45 minutes out of your day today to listen to Bill’s remarkable story. His customized protocol is worth taking seriously!
Bill Curtis developed Parkinson’s symptoms at the age of 45 in the year 2000. He discusses his experience with using ketones as well as other therapies.
Esters are a type of ketone supplement designed to provide the body with an immediate and efficient source of ketones. Ketones are molecules produced by the liver from fatty acids when carbohydrate intake is low. They serve as an alternative energy source to glucose, which is typically derived from carbohydrates. The esters are synthesized through a chemical process that combines ketone bodies with alcohols, resulting in a stable compound that can be consumed as a drink.
Science
When ingested, ketone esters rapidly elevate blood ketone levels, providing a direct source of ketones to fuel your brain and muscles. This is particularly valuable in situations where the body is not producing enough ketones on its own, such as during intense exercise or when following a high-carb diet.
Ketone esters are different from other types of ketone supplements, like ketone salts, due to their more potent and direct effect on blood ketone levels.
Benefits
Enhanced Physical Performance: By increasing the availability of ketones, they provide an alternative energy source that can be utilized during prolonged exercise or high-intensity workouts. Studies have shown that ketone esters can improve endurance, reduce fatigue,and enhance recovery.
Improved Cognitive Function: The brain can benefit from the increased availability of ketones. Research suggests that ketones may offer neuroprotective benefits and improve mental clarity, focus, and cognitive performance.
Metabolic Health: Ketone esters contribute to improved metabolic health. They can help stabilize blood sugar levels and enhance insulin sensitivity. All About Ketone Esters
The following is a comment I received from an individual who “unsubscribed” to my Parkinsons Recovery newsletter today. He solved his problem with magnesium and potassium supplements.
I have enjoyed reading your posts, but my neurologist determined I did not have Parkinson’s.
Symptoms (muscle twitches) were apparently due to Potassium depletion and low Magnesium caused by Blood Pressure drugs and also Carpal Tunnel Syndrome (numbness in hands). Symptoms are mostly gone now.
This is the best news of the day. When neurological symptoms emerge most people assume it will be complicated and involved to silence them. Working in close collaboration with his doctor, this individual found a simple fix to his problem.
Magnesium and Potassium
Magnesium in particular is a fundamental building block of the body. Deficiencies cause a myriad of symptoms. I suggest you do something very simple. Try eating foods that are high in magnesium.
Remember Popeye the sailor man? Popeye ate spinach and he was certainly strong. Spinach is enriched with magnesium. Black beans and pumpkin seeds are good bets too. Of course, magnesium and potassium supplements can also be tried as well.
How about this strategy for a self test: If symptoms improve, chances are good they may be aggravated or even caused by something as simple as a mineral deficiency.
It is now well known that there are a multitude of factors that contribute to the symptoms of Parkinson’s disease. The important questions turns on what is the origin of Parkinson’s disease?
You have likely not heard my answer to this question. At the core resides the real issue at play: The natural life cycle that sustains life is inactive. Instead of flopping back and forth from being expansive and contractive, the state of expansion is s a permanent setting in our energetic “thermostat.” We are on the go constantly without stopping to smell the flowers or enjoy the sweat morsels of the natural world.
We do not function like the ocean waves and tides which shift in and out continuously. The waves flow in and out continuously. Tides gradually shift the waters closer to shore, then more distant from shores.
The root cause of symptoms rarely originates where logic would dictate. Do tremors and other Parkinson’s symptoms originate in the brain? Certainly most people and medical professionals hold this belief. That is why doctors prescribe medications that infuse the body with l-dopa. It is assumed cells in the mid brain are not producing enough dopamine.
Recent research demonstrates that tremors and other neurological challenges do not necessarily reside in the brain itself. Their origin is the digestive system.
Although this research is relatively recent, a causal inspection of meridians that are the pathways of energy keeping us alive clearly show many connections between the stomach, small intestine and gall bladder to the brain. Problems with the digestive system will clearly have a direct impact on brain function.
Step back and consider the life cycle of the digestive system. It expands when we eat. It contracts after food has been digested. Our digestive system does not function continuously.
Our personal life style needs to be in sync the natural course of expanding and contracting.
The root cause of Parkinson’s symptoms is that the life cycle needed to sustain health has been truncated. The expansion phase is permanently set with little flexibility. The need is to assert control over everything and everybody without allowing the ebb and flow of life to exist. When we cannot chill out and relax, the primary functions of the body wear out just as gears in a motor eventually grind down.
What is the bottom line? First, get serious about healing your digestive system. Second, get into the flow of life. Enjoy expansions. Welcome contractions.
An abstract of a study included in this post presents evidence that drinking YerbaMate tea protects against developing Parkinsons. Why might this result be found?
Yerba mate tea contains xanthines, such as caffeine and theobromine. These are adenosine receptor antagonists. The tea blocks these receptors which helps protect dopamine-producing neurons.
Yerba mate is rich in antioxidants which combat oxidative stress. This is known to be a factor associated with Parkinsons.
Theobromine and chlorogenic acid, two components found in yerbamate tea, have demonstrated neuro-protective properties in lab studies.
Any teas (and there are many) which are known to have anti-oxidant properties will be beneficial when it comes to averting the symptoms of Parkinsons. Note that this study examines the history of tea drinking over a long period of time and looks at whether there is a probability of developing Parkinsons at a later time.
While the study finds YerbaMate Tea Protects Against Developing Parkinsons, this does not suggest that persons who currently experience symptoms of Parkinsons will necessarily celebrate a reduction in symptoms if they regularly drink Yerbamate Tea. There is certainly no evidence that this would prove harmful and may well offer benefits on some level.
Clin Neuropharmacol. 2022 Jul-Aug;45(4):79-83. Yerbamate Tea Consumption: A Protective Factor in Parkinson Disease
Abstract
Introduction: Little is known about the association between Yerbamate (YMT) tea consumption and Parkinson disease (PD). We determined whether there was an association between YMT tea consumption and PD.
Methods: We conducted a multicenter case-control study in 3 countries (Argentina, Paraguay, and Uruguay). We applied a structured questionnaire about YMT tea consumption history. The survey also included information about factors previously associated with a decreased and increased risk of PD, apart from medical and demographic factors. Odds ratios and 95% confidence intervals were calculated using multivariate unconditional binary logistic regression analysis.
Results: We included 215 cases and 219 controls. The mean age of the cases was 65.6 ± 10.5 years and that of controls was 63.1 ± 10.5 years (P < 0.02). Years of YMT tea consumption, number of liters drunk per day, and amount of YMT used for preparing the infusion were similar between cases and controls (P > 0.05), but not the number of times the YMT was added into the container (P = 0.003) and the YMT tea concentration per serving (P = 0.02). The multivariate analysis showed that YMT tea concentration per serving lowered the risk for PD, independent of potential confounders (odds ratio, 0.62; 95% confidence interval, 0.47-0.84).
Conclusions: This multicenter study highlights the association between an environmental factor, the YMT tea drinking, and PD. Although more evidence from longitudinal studies is needed, the results obtained here points toward a protective effect of the YMT tea concentration per serving on PD.